In children, which lymph nodes are most frequently affected by acute lymphadenitis?

In children, acute lymphadenitis commonly affects the submandibular lymph nodes. This is often due to infections in the oropharyngeal region, where bacteria such as Streptococcus or Staphylococcus can lead to inflammation and enlargement of the submandibular nodes. These nodes are located close to the site of oral and dental infections, making them particularly susceptible to involvement in acute lymphadenitis.

While cervical lymph nodes are also frequently involved due to their proximity to upper respiratory infections and dental issues, the submandibular nodes are specifically highlighted in this context. Furthermore, axillary and inguinal lymph nodes are less commonly affected in pediatric cases of acute lymphadenitis, as they are more associated with infections or conditions in the corresponding extremities or regions, rather than the head and neck, where most pediatric infections tend to initiate.