In the context of acute cervical adenitis, what are the key pathogens for bilateral cases?

In the context of acute cervical adenitis, particularly when considering bilateral cases in pediatric patients, the key pathogens often include adenovirus and cytomegalovirus (CMV). Adenovirus is known for causing a range of infections in children, including those that can lead to respiratory symptoms or conjunctivitis, and it is associated with lymphadenopathy. CMV is also a common viral cause that can lead to lymph node swelling in younger children, especially in the context of immunocompromised states or congenital infections.

Bilateral cervical adenitis suggests a systemic infectious process rather than a localized one, which is typically seen with bacterial infections. While Staphylococcus and Streptococcus can cause bacterial adenitis, they primarily lead to unilateral infections. Mycobacterium and anaerobic bacteria are more associated with chronic or specific infections rather than acute presentations. Finally, most cases linked to HIV and Influenza would not typically present with bilateral cervical adenitis as a primary feature.

Thus, adenovirus and CMV are the correct pair of pathogens associated with bilateral acute cervical adenitis due to their tendency to cause viral infections manifesting with systemic lymphadenopathy, aligning with the presentation observed in such cases.