True or False: Beckwith-Wiedemann syndrome is characterized by macrosomia, macroglossia, and hypoglycemia.

Beckwith-Wiedemann syndrome is indeed characterized by a triad of features that includes macrosomia (excessively large body size) and macroglossia (enlarged tongue). Additionally, individuals with this syndrome are at risk for hypoglycemia, particularly in infancy, due to impaired regulation of insulin and glucose metabolism.

This syndrome has been associated with abnormalities in genomic imprinting, which can lead to the overgrowth patterns seen in affected individuals. The presence of these three characteristics—macrosomia, macroglossia, and hypoglycemia—provides a classic clinical picture of Beckwith-Wiedemann syndrome.

Therefore, the answer is true as it accurately reflects the key features that define the condition.