What are the primary treatments for primary nephrotic syndrome?

The primary treatments for primary nephrotic syndrome focus on controlling symptoms and inducing remission of the disease, primarily through the use of corticosteroids and sodium restriction.

Corticosteroids, such as prednisone, are first-line therapy in managing primary nephrotic syndrome because they help reduce proteinuria, swelling, and other autoimmune components of the disease. This is particularly effective in cases of minimal change disease, the most common form of nephrotic syndrome in children. The goal is to achieve remission, indicated by a decrease in protein levels in the urine and improvement in symptoms like edema.

Sodium restriction is also an important aspect of managing nephrotic syndrome. It helps control edema by reducing fluid retention. This dietary modification complements steroid therapy, promoting better overall fluid balance and reducing the burden on the kidneys.

Thus, the combination of corticosteroids and sodium restriction is integral to the management strategy for primary nephrotic syndrome.