What are the three risks associated with DiGeorge Syndrome in neonates?

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DiGeorge Syndrome is a genetic disorder that results from a deletion in chromosome 22 and is characterized by a range of medical issues due to developmental defects in the third and fourth pharyngeal pouches. One of the key risks in neonates with this syndrome includes hypoparathyroidism, which can lead to low calcium levels and manifest as tetany, characterized by muscle spasms and cramping due to neuromuscular irritability.

Seizures are another significant risk due to electrolyte imbalances or structural brain abnormalities that may arise in affected individuals. Arrhythmias can occur as a result of congenital heart defects, which are commonly associated with DiGeorge Syndrome. Cardiac issues could lead to disruptions in the heart's normal rhythm, further presenting as arrhythmias.

The combination of tetany, seizures, and arrhythmias encompasses the critical effects of this syndrome that require careful monitoring and management in neonates to mitigate serious complications.

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