What characteristic often accompanies myotonic muscular dystrophy in patients?

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Myotonic muscular dystrophy, particularly type 1 (DM1), is associated with various systemic complications due to its multi-system involvement. One of the significant concerns in patients with myotonic dystrophy is the prevalence of cardiac arrhythmias. This condition often leads to difficulties in the conduction system of the heart, which can manifest as arrhythmias such as atrial fibrillation or bradycardia. The underlying mechanism involves the accumulation of toxic RNA molecules that disrupt normal cellular function, including cardiac muscle cells.

Regular cardiac monitoring is crucial in these patients to identify and manage any potential arrhythmias early, as they can lead to severe complications. Overall, the association of cardiac arrhythmias underscores the importance of a comprehensive approach to managing myotonic muscular dystrophy, beyond the muscular manifestations.

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