What constitutes the classic triad of Kartagener syndrome?

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The classic triad of Kartagener syndrome includes situs inversus, recurrent sinusitis, and bronchiectasis. This condition is a genetic disorder that results from a defect in the ciliary function of cells, leading to the improper clearing of mucus and pathogens from the respiratory tract. As a consequence of these impaired cilia, individuals with Kartagener syndrome often experience chronic respiratory issues, which manifest as recurrent sinusitis and bronchiectasis—a condition characterized by the abnormal dilation and scarring of the airways due to inflammation and infection.

Situs inversus refers to a condition where the major visceral organs are reversed or mirrored from their normal positions, which is a significant feature of Kartagener syndrome. The combination of these three components—abnormal organ placement, respiratory infections, and bronchial changes—forms the hallmark presentation of the syndrome.

Other options include symptoms and findings characteristic of different conditions, but they do not align with the classic triad associated with Kartagener syndrome. The correct answer encapsulates the specific triad that provides insight into the underlying pathophysiology of the condition.

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