What is a known risk factor associated with intestinal atresia?

Intestinal atresia is a congenital condition characterized by an obstruction or closure of a segment of the intestinal tract. Prenatal exposure to substances, particularly those affecting fetal development, is considered a significant risk factor for various congenital anomalies, including intestinal atresia.

In this context, prenatal exposure to cocaine has been associated with increased risks of gastrointestinal tract malformations in the developing fetus. Cocaine use during pregnancy can lead to vascular disruptions and other developmental issues that may result in conditions such as intestinal atresia.

Recognizing this association is crucial for understanding the broader implications of prenatal substance exposure, as it highlights the importance of maternal health and the prenatal environment on fetal development. The other factors listed do not have the same level of established correlation with intestinal atresia, making prenatal cocaine exposure the most recognized risk factor in this scenario.