What syndrome is associated with Wilms tumor?

Beckwith-Wiedemann syndrome is the correct answer because it is a well-recognized overgrowth disorder that has a strong association with Wilms tumor, which is a type of kidney cancer that primarily affects children. The syndrome is characterized by features such as macroglossia (enlarged tongue), hemihyperplasia (asymmetrical growth of one side of the body), and various other congenital anomalies.

Children with Beckwith-Wiedemann syndrome often require regular surveillance for Wilms tumor due to this increased risk, especially in the first few years of life. The link between these two conditions highlights the importance of genetic predispositions in pediatric oncology, as certain syndromes can predispose individuals to specific types of cancers.

Other syndromes mentioned, while they may include cancer risks or other anomalies, are not directly associated with an increased risk of Wilms tumor in the same way that Beckwith-Wiedemann syndrome is.