Which of the following is NOT a symptom of serum sickness-like reaction?

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A serum sickness-like reaction is an immune-mediated hypersensitivity response that typically occurs after exposure to certain medications or antigens. It shares similarities with classical serum sickness but usually has a more rapid onset and can occur without the use of serum from animals. Key symptoms often include joint pain, skin rashes, and fever.

Joint pain is common in serum sickness-like reactions due to the immune complex formation, which can lead to inflammation in the joints. Skin rashes are also prevalent, often presenting as urticaria or other types of dermatitis as the body's immune system reacts. Fever is another typical systemic symptom reflecting the immune response triggered by the antigen.

Elevated LDL, on the other hand, is not a recognized symptom of serum sickness-like reactions. While inflammatory processes can potentially influence lipid metabolism, an increase in LDL levels is not a direct or characteristic symptom associated with this condition. Thus, this choice stands out as the correct answer as it does not fit the symptom profile associated with serum sickness-like reactions.

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