Which of the following is NOT a clinical manifestation of Kawasaki disease?

Kawasaki disease is characterized by a variety of clinical manifestations, primarily involving a prolonged fever and systemic inflammation. The hallmark symptoms include conjunctivitis, which can be bilateral and nonexudative, as well as cervical lymphadenopathy (often painful), and distinct skin changes such as an erythematous rash and desquamation on the palms and soles.

While coughing and wheezing might suggest respiratory involvement, these symptoms are not typical manifestations of Kawasaki disease itself. Instead, they are more associated with respiratory infections or conditions such as asthma, rather than the vasculitis and systemic symptoms seen in Kawasaki disease.

In summary, the presence of conjunctivitis, lymphadenopathy, and skin findings aligns with the classic clinical features of Kawasaki disease, whereas coughing and wheezing do not fit this pattern, marking them as symptoms unrelated to the disease.