Which of the following statements about Wilms' tumor is true?

Wilms' tumor, also known as nephroblastoma, is primarily a pediatric kidney cancer that typically occurs in children, particularly between the ages of 2 and 5 years. This tumor is the most common type of kidney cancer in children, making the statement about its prevalence in children accurate and relevant to its classification as a childhood malignancy.

In contrast to adult cancers, which can have various underlying causes and risk factors, Wilms' tumor is associated with specific genetic syndromes, such as WAGR syndrome and Beckwith-Wiedemann syndrome (BWS), indicating that it is indeed a condition linked to children rather than older adults. The implication of the tumor being predominantly seen in a younger demographic highlights its role in pediatric oncology.

While there are rare instances of Wilms' tumor appearing outside its common age group, its overall characterization as a childhood cancer is a crucial aspect of understanding this disease. Therefore, recognizing Wilms' tumor's primary occurrence in children is essential for appropriate diagnosis, management, and counseling for affected families.